코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Dihydrochelerythrine

다른이름들 

Dihydrotoddaline Toddalinine 12,13-Dihydroxy-1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]-phenanthridine

함유 천연물 

Chelidonium majus L.[]()

분 자 식 

C₂₁H₁₉NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

349.39

녹 는 점 

169-171°C C6H6

UV_CHART 

(λmax, nm) (EtOH):227(4.53), 282(4.65), 318(4.18), 350 sh(3.52)

HNMR_CHART 

(CDCl3,100 MHz) δ:7.71(1H, s, H1), 7.10(1H, s, H4), 7.47(1H, d, 8, H5), 7.69(1H, d, 8, H6), 4.28(1H, s, H8), 6.92(1H, d, 8, H11), 7.50(1H, d, 8, H12), 2.56(3H, s, NMe), 3.88(3H, s, 9-OMe), 3.84(3H, s, 10-OMe), 6.01(2H, s, OCH2O)

MASS_CHART 

M+= 349, m/z= 348, 247, 333, 332, 318, 305, 304, 290

참고문헌 

· BD. Krane et al., J. Nat. Prod., 47, 1, 1984 · L. Slavikova et al., Chem. Listy, 49, 1546, 1955; CA, 50, 4990h · TR. Govindachari et al., J. Chem. Soc., 769, 1956 · PJ. Scheuer et al., J. Org. Chem., 27, 1472, 1962 · PD. Desai et al., Indian J. Chem., 5, 41, 1967 · M. Onda et al., Chem. Pharm. Bull., 18, 1435, 1970 (pmr) · N. Weber, Chem. Ber., 106, 3769, 1973 · BA. Dadson et al., J. Chem. Soc. Perkin Trans. 1, 146, 1976 · J. Slavik et al., Coll. Czech. Chem. Comm., 42, 2686, 1976 · FY. Chou et al., Heterocycles, 7, 969, 1977 · AI. Gray et al., Phytochemistry, 16, 1017, 1977 · JA. Swinehart et al., Phytochemistry, 19, 1219, 1980 · KhSh. Khusainova et al., Khim. Prir. Soedin., 17, 670, 1981; CA, 96, 65673y · SM. Oechslin et al., J. Nat. Prod., 54, 519, 1991