▣ 천연물에서 분리된 개별유효성분 레코드 등록정보
성 분 명
(+)-5-alpha,9-alpha-Dihydroxymatrine
다른이름들
5,9-Dihydroxymatridin-15-one ((+)-form)
Sophoranol ((+)-form); 9alpha-Hydroxy
Sofranol; 9alpha-Hydroxy
5-Hydroxymatrine; 9alpha-Hydroxy
5-alpha-Hydroxymatrine ((+)-form); 9alpha-Hydroxy
함유 천연물
Sophora flavescens Solander ex Aiton[고삼(Go-sam)](고삼(苦蔘),고삼실(苦蔘實),수괴(水槐),지괴(地槐))
분 자 식
C1 5 H2 4 N2 O3
화학족 분류
알칼로이드(alkaloid) ;
분 자 량
280.37
녹 는 점
192-193°C Me2CO
굴 절 율
[α]20 D = +40.6° (C 0.17,EtOH)
HNMR_CHART
(CDCl3,100 MHz) δ:4.31(1H, dd, 13.5, 1, H17 eq.), 3.79(1H, m, H11), 3.67(1H, m, H9), 3.17(1H, d, 13.5, H17 ax.), 3.05(1H, br dd, 10, 4, H10 eq.), 2.78(1H, br d, 10, H2 eq.)
CNMR_CHART
(CDCl3,25 MHz) δ: 56.3, 22.5, 36.9, 68.0, 37.2, 38.4, 35.0, 62.7, 34.0, 53.8, 26.8, 18.6, 32.6, 171.2, 46.5
MASS_CHART
M+= 280, m/z= 263, 221, 112, 55(100)
참고문헌
· S. Ohmiya et al., Phytochemistry, 18, 645, 1979(ir,pmr,cmr,ms)
· F. Bohlmann et al., Chem. Ber., 91, 2189, 1958
· S. Okuda et al., Chem. Pharm. Bull., 13, 482, 1965
· S. Ohmiya et al., Phytochemistry, 18, 648, 1978
· I. Murakoshi et al., Phytochemistry, 21, 2379, 1982
