코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Stylopine

다른이름들 

Tetrahydrocopitisine 6,7,12b,13-Tetrahydro-4H-bis[1,3]benzodioxolo[5,6-a:4',5'-g]quinoline

함유 천연물 

Chelidonium majus L.[]()
Corydalis turtschaninovii Fa yanjusuo[]()

분 자 식 

C₁₉H₁₇NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

323.352

녹 는 점 

217-218°C

생리학적효과 

Antipsychotic and neuroleptic activity in mice and rats.

UV_CHART 

(λmax, nm) (MeOH):289.4

HNMR_CHART 

δ:2.64(2H, m, H5,6), 2.79 & 3.22(2H, qd, H13), 3.1(2H, m, H5,6), 3.52, 4.09(2H, q, H8), 3.56(1H, dd, H14), 5.92(2H, s, OCH2O), 5.92, 5.96(2H, q, OCH2O), 6.59(1H, s, ArH), 6.63(1H, d, ArH), 6.68(1H, d, ArH), 7.3(1H, s, ArH)

CNMR_CHART 

δ: 2.96, 36.5, 51.2, 52.9, 59.8, 100.7, 101.1, 105.5, 106.7, 108.4,116.9, 121.0, 127.8, 128.6, 130.8, 145.0, 146.0, 146.2

참고문헌 

· E. Spath et al., Ber., 64, 1131, 1931 · G. Dai-Ho et al., J. Org. Chem., 53, 5113, 1988(uv,ir,pmr,cmr) · PW. Jeffs et al., J. Org. Chem., 40, 644, 1975 · AR. Battersby et al., J. Chem. Soc. Perkin Trans. 1, 1140, 1975 · SK. Bhattacharya et al., Arzneim.-Forsch., 26, 2187, 1976 · N. Takao et al., Chem. Pharm. Bull., 24, 3185, 1976 · NS. Narasimhan et al., Tetrahedron, 39, 1975, 1983 · DS. Bhakuni et al., Alkaloids (N.Y.), 28, 95, 1986 · E. Taborska et al., Coll. Czech. Chem. Comm., 51, 2232, 1986 · M. Chrzanowska, J. Nat. Prod., 58, 401, 1995