코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

1-Carbomethoxy-4-methoxy-beta-carboline

다른이름들 

Methyl 4-methoxy-beta-carboline-1-carboxylate 4-Methoxy-beta-carboline-1-carboxylic acid methyl ester 4-Methoxy-beta-carboline 1-carboxylic acid methyl ester

함유 천연물 

Ailanthus altissima (Mill.) Swingle for. altissima[가죽나무(Ga-jung-na-mu)](저백피(樗白皮))

분 자 식 

C₁₄H₁₂N₂O₃

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

256.263

녹 는 점 

pale yell. 191-192°C

UV_CHART 

(λmax, nm) (EtOH):235.5(4.32), 246.5(4.29), 266.5(4.41), 277.5(4.31), 303(3.94), 362.5(3.87)

HNMR_CHART 

(CDCl3,100 MHz) δ:4.10(3H, s, COOMe-1), 4.23(3H, s, 4-OMe), 7.21-7.58(3H, m, H6,7,8), 8.19(1H, s, H3), 8.29(1H, d, 8, H5), 9.88(1H, br s, NH)

MASS_CHART 

M+= 256, m/z= 250(100), 225, 224, 198, 196, 182, 181, 154, 153, 127, 126, 99

참고문헌 

· T. Ohmoto et al., Chem. Pharm. Bull., 24, 1532, 1976(uv,ir,pmr,ms) · E. Varga et al., Planta Med., 40, 337, 1980 · HR. Snyder et al., J. Am. Chem. Soc., 71, 527, 1949 · C. Kump et al., Helv. Chim. Acta, 46, 498, 1963 · H. Achenbach et al., J. Am. Chem. Soc., 87, 4177, 1965 · E. Sanchez et al., Phytochemistry, 10, 2155, 1971 · S. McLean et al., Can. J. Chem., 50, 1478, 1972 · Y. Kondo et al., Chem. Pharm. Bull., 21, 837, 1973 · BS. Joshi et al., Heterocycles, 7, 193, 1977 · T. Ohmoto et al., Chem. Pharm. Bull., 32, 3579, 3583, 1984 · K. Koike et al., Org. Magn. Reson., 22, 471, 1984