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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Mesaconitine |
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다른이름들 |
N-Desethyl-N-methylaconitine
Japaconitine A
Japaconitine B |
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함유 천연물 |
Aconitum carmichaeli Deb.[오두(烏頭)](부자(附子),흑순편(黑順片),백부편(白附片),염부자(鹽附子))
Aconitum ciliare DC.[선덩굴바꽃(Seon-deong-gul-ba-kkot)](초오(草烏))
Aconitum kusnezoffii Rchb.[이삭바꽃(I-sak-ba-kkot)]()
Aconitum proliferum Nakai[싹눈바꽃(Ssang-nun-ba-kkot)]() |
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분 자 식 |
C33H45NO11 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
631.727 |
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녹 는 점 |
208-209(dec.)°C |
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굴 절 율 |
[α]17 D = +25.4°( CHCl3) |
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UV_CHART |
(λmax, nm) (EtOH):232 |
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HNMR_CHART |
δ:1.43(3H, s, OCOCH3), 2.59(3H, s, NMe), 3.32 and 3.88(ea. 3H, s, OMe), 3.43(6H, s, OMe), 4.92(1H, d, 5, H14beta), 7.38-8.20(aromatic protons) |
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CNMR_CHART |
(CDCl3,25 MHz) δ: 83.2, 35.9, 70.8, 43.5, 46.5, 82.4, 44.3, 91.8, 43.8, 40.9, 50.0, 34.2, 74.1, 78.9, 78.9, 90.1, 62.2, 75.8, 49.4, 42.4, 56.2, 57.9, 61.0, 59.0, 172.3, 21.4, 166.0, 129.9, 129.6, 128.6, 133.2 |
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참고문헌 |
· SW. Pelletier et al., J. Am. Chem. Soc., 98, 2626, 1976
· K. Hatano et al., Planta Med., 54, 2, 152, 1988
· SY. Chen et al., Yun Nan Chih Wu Yen Chiu, 4, 1, 73, 1982; CA, 97, 20745, C(uv)
· S. Morio, Annalen, 476, 181, 1929
· M. Przybylska et al., Can. J. Chem., 37, 1116, 1843, 1959
· FW. Bachelor et al., Tetrahedron Lett., No. 10, 1, 1960
· KB. Birnbaum et al., Tetrahedron Lett., 867, 1971 |
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