코스넷:::::화장품원료:::::

 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Isoboldine; (S)-form

다른이름들 

N-Methylaurelliptine 1,9-Dihydroxy-2,10-dimethoxyaporphine

함유 천연물 

Cinnamomum camphora (L.) J.Presl[녹나무(Nong-na-mu)](장뇌(樟腦),장목(樟木),뇌자(腦子),소뇌(小腦),소뇌(昭腦))
Cocculus trilobus (Thunb.) DC.[댕댕이덩굴(Daeng-daeng-i-deong-gul)](목방기(木防己),방기(防己))
Lindera strychinifolia (Sieb. et Zucc.) F. Vill.[오약](오약(烏藥),천태오약(天台烏藥))
Nandina domestica Thunb.[남천(Nam-cheon)](남천죽자(南天竹子),남천죽엽(南天竹葉),남천죽근(南天竹根))
Zizyphus jujuba Mill. var. jujuba[묏대추나무(Moet-dae-chu-na-mu)](산조인(酸棗仁))

분 자 식 

C₁₉H₂₁NO₄

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

327.384

녹 는 점 

178-180(dec.)°C

생리학적효과 

Antifeedant, insecticide

굴 절 율 

[α]13 D = +54° (C 0.2,EtOH)

UV_CHART 

(λmax, nm) (EtOH):219(4.58), 268 sh(4.08), 280(4.16), 304(4.21), 313(4.18)

HNMR_CHART 

(CDCl3,100 MHz) δ:6.46(s,H3), 6.72(s,H8), 7.95(s,H11), 3.86(s,OMe), 3.86(s,OMe), 3.86(s,OMe), 2.52(s,NMe)

CNMR_CHART 

(DMSO-d6,15 MHz) δ: 140.6, 119.7, 123.5, 146.5, 109.2, 126.7, 28.4, 52.9, 62.4, 33.7, 129.1, 114.9, 145.4, 145.3, 113.6, 123.0, 43.6, 55.8, 55.8

MASS_CHART 

M+= 327, m/z= 326, 312, 296, 284, 269, 253

참고문헌 

· AH. Jackson et al., J. Chem. Soc.(C), 2061, 1966(uv,pmr) · H. Guinaudeau et al., J. Nat. Prod., 38, 275, 1975; 42, 325, 1979 · R. Ziyaev et al., Khim. Prir. Soedin., 13, 239, 1977 · Y. Sawada et al., Shoyakugaku Zasshi, 46, 2, 143, 1992 · PS. Clezy et al., Aust. J. Chem., 19, 135, 1966 · SR. Johns et al., Aust. J. Chem., 19, 2331, 1966 · WWC. Chan et al., J. Chem. Soc.(C), 753, 1966 · J. Slavik, Coll. Czech. Chem. Comm., 33, 323, 1968 · K. Wada et al., J. Agric. Food Chem., 16, 471, 1968 · J. Kunitomo et al., Yakugaku Zasshi, 94, 1149, 1974; CA, 82, 14024r · GM. Brown et al., Acta Cryst. B, 33, 2051, 1977 · T. Kametani et al., J. Am. Chem. Soc., 99, 3805, 1977 · GS. Ricca et al., Gazz. Chim. Ital., 109, 1, 1979