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 ▣ 천연물에서 분리된 개별유효성분 레코드 등록정보

성 분 명 

Ignavine

다른이름들 

Hetisan-2,3,9,15-tetrol 2-benzoate

함유 천연물 

Aconitum carmichaeli Deb.[오두(烏頭)](부자(附子),흑순편(黑順片),백부편(白附片),염부자(鹽附子))

분 자 식 

C₂₇H₃₁NO₅

화학족 분류 

알칼로이드(alkaloid);

분 자 량 

449.552

녹 는 점 

172-173°C CHCl3

굴 절 율 

[α]D = +47.0°(C 0.2, MeOH)

HNMR_CHART 

(CD3OD,100 MHz) δ:1.17(3H,s,C-CH3), 4.99(2H,br s,C=CH2), 5.39(1H,br s,CHOCO), 7.54(3H,m), 7.99(2H,dd,8,2)

CNMR_CHART 

(CD3OD,25 MHz) δ: 25.7, 25.7, 30.0, 34.3, 36.3, 39.7, 42.2, 43.2, 45.4, 51.5, 52.1, 62.4, 65.7, 71.3, 73.0, 74.7, 75.8, 80.1, 110.2, 129.8, 130.2, 130.4, 134.4, 155.6, 166.8

MASS_CHART 

M+= 449

참고문헌 

· E. Ochiai et al., Yakugaku Zasshi, 76, 550, 1956 · H. Hikino et al., J. Nat. Prod., 46, 178, 1983 · E. Ochiai et al., Chem. Pharm. Bull., 7, 556, 1959 · SW. Pelletier et al., Tetrahedron Lett., 4825, 1970 · T. Okamoto et al., Chem. Pharm. Bull., 30, 4600, 1982 · H. Takayama et al., Yakugaku Zasshi, 102, 525, 1982; CA, 97, 141690q · T. Okamoto et al., Chem. Pharm. Bull., 31, 360, 1983 · H. Takayama et al., Chem. Pharm. Bull., 36, 3210, 1988