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▣ 천연물에서 분리된 개별유효성분 레코드 등록정보 |
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성 분 명 |
Glaucine |
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다른이름들 |
O-Methylthalicmidine
Boldine dimethyl ether
1,2,9,10-Tetramethoxyporphine |
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함유 천연물 |
Corydalis yanhusuo W. T. Wang[](연호색(延胡索)) |
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분 자 식 |
C21H25NO4 |
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화학족 분류 |
알칼로이드(alkaloid); |
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분 자 량 |
355.438 |
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생리학적효과 |
Antithrombotic, analgesic and antiinflammatory activity. Antifungal agent. Produces narcosis and convulsions in animals, also hypotension and respiratory depression. Antitussive agent with similar potency to Codeine. Mild muscle relaxant. |
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UV_CHART |
(λmax, nm) (EtOH):218(4.58), 281(4.18), 303(4.16) |
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HNMR_CHART |
(CDCl3,600 MHz) δ:3.12(H4 alpha), 2.67(H4 beta), 3.02(H5 alpha), 2.45(H5 beta), 3.03(H6a), 3.01(H7 alpha), 2.57(H7 beta) |
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CNMR_CHART |
(CDCl3) δ: 144.2, 126.8, 127.2, 151.8, 110.4, 128.8, 29.2, 53.3, 43.4, 62.5, 34.5, 129.3, 110.9, 148.0, 147.4, 111.6, 124.4 |
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MASS_CHART |
M+= 355, m/z= 354, 340, 338, 324, 297, 281 |
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참고문헌 |
· K. Suto et al., Chem. Pharm. Bull., 33, 12, 5369, 1985
· T. Hu et al., Nan-Ching Yao Hsueh Yuan Hsueh Pao, 16, 2, 7, 1985
· KM. Kerr et al., J. Nat. Prod., 49, 576, 1986(pmr)
· M. Shamma et al., J. Nat. Prod., 42, 437, 1979(cmr)
· A. Cave et al., J. Nat. Prod., 38, 275, 1975(uv,ir,ms) |
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